San Francisco 49ers 2025 Schedule Release Date. Espn has the full 2025 san francisco 49ers regular season nfl schedule. San francisco will face each of their 2023 postseason opponents in the 2025 regular season [green bay (week 12), detroit (week 17) and kansas city (week 7)].
Kansas city is coming off. The 49ers 2025 schedule has been officially announced.
